Open AccessNext-generation sequencing of the cerebrospinal fluid in the diagnosis of neurobrucellosis
Author(s) -
Siyuan Fan,
Haitao Ren,
Yanping Wei,
Chenhui Mao,
Zhenzi Ma,
Lu Zhang,
Li Wang,
Ying Ge,
Taisheng Li,
Liying Cui,
Honglong Wu,
Hongzhi Guan
Publication year - 2017
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2017.11.028
Subject(s) - cerebrospinal fluid , medicine , brucellosis , brucella , dna sequencing , immunology , biology , gene , biochemistry
Brucellosis is the most common zoonotic infection in the world. Brucellosis with nervous system involvement is known as 'neurobrucellosis' (NB). The diagnosis of NB is difficult because its clinical manifestations are non-specific and the sensitivity of routine culture tests is low.
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