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High diversity of multidrug-resistant Mycobacterium tuberculosis Central Asian Strain isolates in Nepal
Author(s) -
Yogendra Shah,
Bhagwan Maharjan,
Jeewan Thapa,
Ajay Poudel,
Hassan Mahmoud Diab,
Basu Dev Pandey,
Eddie Samuneti Solo,
Norikazu Isoda,
Yasuhiko Suzuki,
Chie Nakajima
Publication year - 2017
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2017.06.010
Subject(s) - rpob , mycobacterium tuberculosis , biology , variable number tandem repeat , tuberculosis , genotype , typing , molecular epidemiology , rifampicin , multiple drug resistance , genetic diversity , outbreak , transmission (telecommunications) , virology , drug resistance , genetics , microbiology and biotechnology , medicine , antibiotics , gene , population , environmental health , pathology , electrical engineering , engineering
Tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB) poses a major public health problem in Nepal. Although it has been reported as one of the dominant genotypes of MTB in Nepal, little information on the Central Asian Strain (CAS) family is available, especially isolates related to multidrug resistance (MDR) cases. This study aimed to elucidate the genetic and epidemiological characteristics of MDR CAS isolates in Nepal.

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