Receipt of thyroid hormone deficiency treatment and risk of herpes zoster | Zendy

S. Victor Hsia | Zendy; Lie Hong Chen | Zendy; Hung Fu Tseng | Zendy

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Receipt of thyroid hormone deficiency treatment and risk of herpes zoster

Author(s) -

S. Victor Hsia,

Lie Hong Chen,

Hung Fu Tseng

Publication year - 2017

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2017.04.016

Subject(s) - medicine , hazard ratio , hormone , thyroid , confidence interval , varicella zoster virus , cohort , pediatrics , virus , immunology

Thyroid hormone (TH) has been suggested to control herpes virus gene expression and replication in neurons via epigenetics through its nuclear receptors. It has previously been shown that patients with hypothyroidism are predisposed to herpes zoster (HZ), suggesting that the TH deficiency may be a risk factor for varicella zoster virus (VZV) reactivation. The aim of this study was to test the hypothesis that TH treatment will ameliorate the complication of HZ.

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