The clinical significance of neutrophilic pleocytosis in cerebrospinal fluid in patients with viral central nervous system infections | Zendy

Siraya Jaijakul | Zendy; Lucrecia Salazar | Zendy; Susan H. Wootton | Zendy; Elizabeth Aguilera | Zendy; Rodrigo Hasbun | Zendy

Open Access

The clinical significance of neutrophilic pleocytosis in cerebrospinal fluid in patients with viral central nervous system infections

Author(s) -

Siraya Jaijakul,

Lucrecia Salazar,

Susan H. Wootton,

Elizabeth Aguilera,

Rodrigo Hasbun

Publication year - 2017

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2017.04.010

Subject(s) - pleocytosis , csf pleocytosis , medicine , cerebrospinal fluid , clinical significance , lymphocytic pleocytosis , immunology , gastroenterology , pathology , encephalitis , virus

Viral central nervous system (CNS) infections are typically characterized by a cerebrospinal fluid (CSF) lymphocytic pleocytosis. A CSF neutrophilic pleocytosis presentation has been described, but its prognostic and clinical significance is unknown. The objectives of this study were to (1) compare the clinical and laboratory characteristics of viral CNS infections with a CSF neutrophilic pleocytosis to those with a lymphocytic pleocytosis, and (2) evaluate factors associated with an adverse clinical outcome.

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