Decrease in regulatory T-cell function in chronic hepatitis C patients receiving pegylated-interferon plus ribavirin | Zendy

KuoChih Tseng | Zendy; Yun-Che Ho | Zendy; Chi-Wei Tseng | Zendy; Ling-Huei Tseng | Zendy; Yu-Hsi Hsieh | Zendy; TingTsung Chang | Zendy; ShuFen Wu | Zendy

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Decrease in regulatory T-cell function in chronic hepatitis C patients receiving pegylated-interferon plus ribavirin

Author(s) -

KuoChih Tseng,

Yun-Che Ho,

Chi-Wei Tseng,

Ling-Huei Tseng,

Yu-Hsi Hsieh,

TingTsung Chang,

ShuFen Wu

Publication year - 2017

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2017.02.015

Subject(s) - ribavirin , immunosuppression , medicine , pegylated interferon , combination therapy , gastroenterology , alanine transaminase , immunology , liver function , hepatitis c , chronic hepatitis , virus

Regulatory T-cells (Tregs) play an important role in the pathogenesis of chronic hepatitis C (CHC) infection. Pegylated interferon is the standard therapy for CHC patients in Asian countries. This study aimed to evaluate the frequency and function of Tregs in CHC patients receiving combination therapy.

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