Open AccessZika virus shedding in human milk during lactation: an unlikely source of infection?
Author(s) -
Marta Guimarães Cavalcanti,
Mauro Jorge CabralCastro,
Jorge Luiz S. Gonçalves,
Larissa S. Santana,
Eduardo Pimenta,
José Mauro Peralta
Publication year - 2017
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2017.01.042
Subject(s) - zika virus , viremia , virology , transmission (telecommunications) , sexual transmission , breast milk , chikungunya , virus , biology , viral shedding , breastfeeding , breast feeding , isolation (microbiology) , medicine , immunology , pediatrics , microbiology and biotechnology , human immunodeficiency virus (hiv) , biochemistry , microbicide , electrical engineering , engineering
Zika virus (ZIKV) transmission through non-mosquito-dependent routes has become increasingly important since reports of sexual transmission. Breastfeeding is a potential means of ZIKV transmission, but data on this remain limited. The cases of four mothers with laboratory-proven infections are reported. No disease evolved in three of the breastfed babies despite detectable maternal viremia and viruria, the presence of viral RNA shedding, and the isolation of infective particles in one milk sample. Fever and rash in one infant of a ZIKV-infected mother proved to be related to chikungunya virus infection. The results suggest that the presence of infective particles in breast milk may not be sufficient for the efficient perinatal transmission of ZIKV.
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