Peptide microarray-based characterization of antibody responses to host proteins after bacille Calmette–Guérin vaccination | Zendy

Davide Valentini | Zendy; Martin Rao | Zendy; Lalit Rane | Zendy; Sayma Rahman | Zendy; Rebecca AxelssonRobertson | Zendy; Rainer Heuchel | Zendy; Matthias Löhr | Zendy; Daniel F. Hoft | Zendy; Susanna Brighenti | Zendy; Alimuddin Zumla | Zendy; Markus Maeurer | Zendy

Open Access

Peptide microarray-based characterization of antibody responses to host proteins after bacille Calmette–Guérin vaccination

Author(s) -

Davide Valentini,

Martin Rao,

Lalit Rane,

Sayma Rahman,

Rebecca AxelssonRobertson,

Rainer Heuchel,

Matthias Löhr,

Daniel F. Hoft,

Susanna Brighenti,

Alimuddin Zumla,

Markus Maeurer

Publication year - 2017

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2017.01.027

Subject(s) - immunology , vaccination , immune system , biology , medicine

Bacille Calmette-Guérin (BCG) is the world's most widely distributed vaccine, used against tuberculosis (TB), in cancer immunotherapy, and in autoimmune diseases due to its immunomodulatory properties. To date, the effect of BCG vaccination on antibody responses to host proteins has not been reported. High-content peptide microarrays (HCPM) offer a unique opportunity to gauge specific humoral immune responses.

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