Immune recognition surface construction of Mycobacterium tuberculosis epitope-specific antibody responses in tuberculosis patients identified by peptide microarrays
Author(s) -
Davide Valentini,
Martin Rao,
Giovanni Ferrara,
Marc Perkins,
Ernest Dodoo,
Alimuddin Zumla,
Markus Maeurer
Publication year - 2017
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2017.01.015
Subject(s) - epitope , tuberculosis , mycobacterium tuberculosis , immune system , antigen , immunology , antibody , biology , virology , medicine , pathology
Understanding of humoral immune responses in tuberculosis (TB) is gaining interest, since B-cells and antibodies may be important in diagnosis as well as protective immune responses. High-content peptide microarrays (HCPM) are highly precise and reliable for gauging specific antibody responses to pathogens, as well as autoantigens.
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