Cerebral Rhizomucor Infection Treated by Posaconazole Delayed-Release Tablets in an Allogeneic Stem Cell Transplant Recipient | Zendy

Diego O. Andrey | Zendy; Laurent Kaiser | Zendy; Stéphane Emonet | Zendy; Véronique Erard | Zendy; Yves Chalandon | Zendy; Christian van Delden | Zendy

Open Access

Cerebral Rhizomucor Infection Treated by Posaconazole Delayed-Release Tablets in an Allogeneic Stem Cell Transplant Recipient

Author(s) -

Diego O. Andrey,

Laurent Kaiser,

Stéphane Emonet,

Véronique Erard,

Yves Chalandon,

Christian van Delden

Publication year - 2016

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2016.12.014

Subject(s) - posaconazole , zygomycosis , medicine , mucormycosis , hematopoietic stem cell transplantation , amphotericin b , dermatology , transplantation , surgery , antifungal

Mucormycosis (zygomycosis) is an emerging fungal disease in allogeneic hematopoietic stem cell transplant (allo-HSCT) recipients. A 30-year-old woman diagnosed with acute myelomonocytic leukemia and needing allo-HSCT presented pulmonary and cerebral infection due to Rhizomucor pusillus. This fungal infection was treated with surgical treatment and posaconazole delayed-release tablets. This strategy allowed reaching high drug levels that could not be obtained with the posaconazole solution.

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