Open AccessPoblational and biochemical-structural analyses on CTX-M β-lactamases harboring the D240G mutation reveal that E. coli populations with decreased susceptibility to ceftazidime preexist under a multifactorial resistance profile
Author(s) -
Bárbara Ghiglione,
M.M. Rodríguez,
Florencia Brunetti,
Milena Dropa,
Lucrecia M. Curto,
P.P. Power,
Gabriel Gutkind
Publication year - 2016
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2016.11.111
Subject(s) - ceftazidime , cefotaxime , mutant , biology , mutation , microbiology and biotechnology , escherichia coli , enzyme kinetics , plasmid , porin , gene , genetics , enzyme , antibiotics , biochemistry , pseudomonas aeruginosa , bacteria , active site , bacterial outer membrane
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