Utility of the serum galactomannan assay for the diagnosis of invasive aspergillosis in children with acute lymphoblastic leukemia | Zendy

Gülhadiye Avcu | Zendy; Deniz Yılmaz Karapınar | Zendy; Burcu Akıncı | Zendy; Zühal Önder Siviş | Zendy; Akkız Şahin | Zendy; Zümrüt Şahbudak Bal | Zendy; Süleyha Hilmioğlu Polat | Zendy; Dilek Yeşim Metin | Zendy; Fadıl Vardar | Zendy; Yeşim Aydınok | Zendy

Open Access

Utility of the serum galactomannan assay for the diagnosis of invasive aspergillosis in children with acute lymphoblastic leukemia

Author(s) -

Gülhadiye Avcu,

Deniz Yılmaz Karapınar,

Burcu Akıncı,

Zühal Önder Siviş,

Akkız Şahin,

Zümrüt Şahbudak Bal,

Süleyha Hilmioğlu Polat,

Dilek Yeşim Metin,

Fadıl Vardar,

Yeşim Aydınok

Publication year - 2016

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2016.10.027

Subject(s) - galactomannan , medicine , aspergillosis , incidence (geometry) , hematology , acute leukemia , gold standard (test) , lymphoblastic leukemia , cancer , gastroenterology , leukemia , pediatrics , immunology , physics , optics

Invasive aspergillosis (IA) is an important cause of mortality and morbidity in children with hematological malignancies. The monitoring of serum galactomannan (GM) antigen is considered useful in the diagnosis of IA . The aim of this study was to determine the utility of serum GM monitoring in the early diagnosis of IA and the role of positive antigenemia in the management of children with acute lymphoblastic leukemia (ALL).

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