Novel approaches to tuberculosis vaccine development
Author(s) -
Stefan H. E. Kaufmann,
January Weiner,
C. Fordham von Reyn
Publication year - 2016
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2016.10.018
Subject(s) - tuberculosis , medicine , tuberculosis vaccines , virology , bcg vaccine , mycobacterium tuberculosis , infectious disease (medical specialty) , immunology , disease , vaccination , pathology
Tuberculosis (TB) remains the deadliest infectious disease. The widely used bacille Calmette-Guérin (BCG) vaccine offers only limited protection against TB. New vaccine candidates for TB include subunit vaccines and inactivated whole-cell vaccines, as well as live mycobacterial vaccines. Current developments in TB vaccines are summarized in this review.
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