Quantitative intrahepatic HBV cccDNA correlates with histological liver inflammation in chronic hepatitis B virus infection | Zendy

Ling-Bo Liang | Zendy; Xia Zhu | Zendy; Libo Yan | Zendy; Lingyao Du | Zendy; Cong Liu | Zendy; Juan Liao | Zendy; Hong Tang | Zendy

Open Access

Quantitative intrahepatic HBV cccDNA correlates with histological liver inflammation in chronic hepatitis B virus infection

Author(s) -

Ling-Bo Liang,

Xia Zhu,

Libo Yan,

Lingyao Du,

Cong Liu,

Juan Liao,

Hong Tang

Publication year - 2016

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2016.09.022

Subject(s) - cccdna , medicine , hepatitis b virus , liver biopsy , inflammation , gastroenterology , alanine transaminase , odds ratio , liver disease , hepatitis b , immunology , biopsy , hbsag , virus

The aim of this study was to determine the role of baseline hepatitis B virus (HBV) forming covalently closed circular DNA (HBV cccDNA) in liver inflammation in patients infected with HBV with serum alanine aminotransferase (ALT) levels under two times the upper limit of normal (2×ULN).

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