Interactions of linezolid and second-line anti-tuberculosis agents against multidrug-resistant Mycobacterium tuberculosis in vitro and in vivo | Zendy

Weijie Zhao | Zendy; Meiqin Zheng | Zendy; Bin Wang | Zendy; Xiaopan Mu | Zendy; Peng Li | Zendy; Lei Fu | Zendy; Shuo Liu | Zendy; Zhenyong Guo | Zendy

Open Access

Interactions of linezolid and second-line anti-tuberculosis agents against multidrug-resistant Mycobacterium tuberculosis in vitro and in vivo

Author(s) -

Weijie Zhao,

Meiqin Zheng,

Bin Wang,

Xiaopan Mu,

Peng Li,

Lei Fu,

Shuo Liu,

Zhenyong Guo

Publication year - 2016

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2016.08.027

Subject(s) - capreomycin , clofazimine , linezolid , rifampicin , bedaquiline , isoniazid , pyrazinamide , tuberculosis , extensively drug resistant tuberculosis , mycobacterium tuberculosis , medicine , microbiology and biotechnology , pharmacology , ethambutol , biology , vancomycin , immunology , pathology , bacteria , genetics , staphylococcus aureus , leprosy

The objectives of this study were to evaluate the interactions between linezolid (LZD) and second-line anti-tuberculosis (TB) agents in susceptible and multidrug-resistant (MDR) TB in vitro, and to validate the in vitro results in a murine TB model.

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