Optimizing intravenous fosfomycin dosing in combination with carbapenems for treatment of Pseudomonas aeruginosa infections in critically ill patients based on pharmacokinetic/pharmacodynamic (PK/PD) simulation | Zendy

Orarik Asuphon | Zendy; Preecha Montakantikul | Zendy; Jantana Houngsaitong | Zendy; Pattarachai Kiratisin | Zendy; Paveena Sonthisombat | Zendy

Open Access

Optimizing intravenous fosfomycin dosing in combination with carbapenems for treatment of Pseudomonas aeruginosa infections in critically ill patients based on pharmacokinetic/pharmacodynamic (PK/PD) simulation

Author(s) -

Orarik Asuphon,

Preecha Montakantikul,

Jantana Houngsaitong,

Pattarachai Kiratisin,

Paveena Sonthisombat

Publication year - 2016

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2016.06.017

Subject(s) - fosfomycin , carbapenem , pseudomonas aeruginosa , pharmacodynamics , antibiotics , medicine , pharmacokinetics , dosing , minimum inhibitory concentration , pharmacology , microbiology and biotechnology , biology , bacteria , genetics

The purpose of the study was to determine the optimal dosing regimen of intravenous fosfomycin for the treatment of Pseudomonas aeruginosa (PA) based on PK/PD targets.

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