Open AccessIs de-escalation of antimicrobials effective? A systematic review and meta-analysis
Author(s) -
Goh Ohji,
Asako Doi,
Shungo Yamamoto,
Kentaro Iwata
Publication year - 2016
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2016.06.002
Subject(s) - medicine , meta analysis , de escalation , observational study , medline , cochrane library , intensive care medicine , randomized controlled trial , odds ratio , political science , law
De-escalation therapy is a strategy used widely to treat infections while avoiding the use of broad-spectrum antimicrobials. However, there is a paucity of clinical evidence to demonstrate the effectiveness and safety of de-escalation therapy compared to conventional therapy.
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