Application of Pharmacodynamic Profiling for the Selection of Optimal β-lactam Regimens in a Large University Hospital | Zendy

Pornpan Koomanachai | Zendy; Thitiya Yungyuen | Zendy; Pensiri Disthaporn | Zendy; Pattarachai Kiratisin | Zendy; David P. Nicolau | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Application of Pharmacodynamic Profiling for the Selection of Optimal β-lactam Regimens in a Large University Hospital

Author(s) -

Pornpan Koomanachai,

Thitiya Yungyuen,

Pensiri Disthaporn,

Pattarachai Kiratisin,

David P. Nicolau

Publication year - 2016

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2016.03.020

Subject(s) - cefepime , doripenem , ceftazidime , ceftriaxone , meropenem , medicine , cephalosporin , pharmacodynamics , imipenem , carbapenem , antibiotics , minimum inhibitory concentration , microbiology and biotechnology , dosing , pharmacology , pharmacokinetics , biology , antibiotic resistance , pseudomonas aeruginosa , bacteria , genetics

Infections caused by drug-resistant Gram-negative bacteria (GNB) are increasing worldwide and as a result, the selection of appropriate empiric antibiotics (ATBs) has been made increasingly difficult. The present study aimed to identify optimized dosing regimens of intravenous (IV) ATBs, defined by cumulative fraction response (CFR), against E. coli (EC), K. pneumoniae (KP), P. aeruginosa (PA), and A. baumannii (AB) at 2,300-bed University Hospital.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research