Measles among pregnant women in South Kazakhstan in recent times

Background: In recent years, the measles incidence increase has been registered in many regions of Kazakhstan despite the fact that the national program of the infection elimination is in progress. There was its growth by 4,4 times in the Republic and by 2,2 times in the South-Kazakhstan oblast in the year 2014 compared to the year 2013. Goals: comparative analysis of the clinical features and outcomes in pregnant women in South Kazakhstan. Methods & Materials: One hundred medical cases of measles were analyzed among the in-door patients of the infectious disease hospital within the yeas 2014-2015, where adults made up 40 medical cases, children constituted 40 ones and pregnant women made up 20 ones with a different duration of gestation. Results: Severe measles course was observed in 22, 5% of medical cases in children, where it made up 45% in adults and constituted 100% in pregnant women. Fever (more than 38, 5 degrees) was registered in children (72.5% of medical cases) made up 77, 5% in adults and constituted 80% in pregnant women. Maculo-papular rash skinned out in 27, 5% of pregnant women on the third day from the disease onset, it accounted 57,5% in pregnant ones on the 4th 5th day and made up 15% in ones being at a later date. Acute bronchitis (17, 5%), pneumonia (7, 5%), conjunctivitis (5%) and spontaneous miscarriage (8, 3%) were among the complications in pregnant women. The delivery started in all pregnant women on the 2nd-3rd day of hospitalization being at the gestational age of 35-38 weeks (25%) and having acute toxicosis in the period of skin rashes. Conclusion: Clinical course of measles is very severe in pregnant women with apparent toxicosis and some complications occurred. It is the triggering factor for spontaneous miscarriages and premature delivery.