Group A Streptococcus induces less p65 nuclear translocation and non-classical nuclear factor kappa B activation in macrophages, which possibly leads to a weaker inflammatory response | Zendy

Shuhui Wu | Zendy; Cuiqing Ma | Zendy; Xue Gao | Zendy; Ling Zhang | Zendy; Qingfeng Miao | Zendy; Miao Li | Zendy; Wenjian Li | Zendy; Xiaotian Song | Zendy; Xiurong Wang | Zendy; Jianguo Liu | Zendy; Lin Wei | Zendy

Open Access

Group A Streptococcus induces less p65 nuclear translocation and non-classical nuclear factor kappa B activation in macrophages, which possibly leads to a weaker inflammatory response

Author(s) -

Shuhui Wu,

Cuiqing Ma,

Xue Gao,

Ling Zhang,

Qingfeng Miao,

Miao Li,

Wenjian Li,

Xiaotian Song,

Xiurong Wang,

Jianguo Liu,

Lin Wei

Publication year - 2016

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2016.01.018

Subject(s) - western blot , tlr4 , p50 , nf κb , transcription factor , signal transduction , chemistry , nfkb1 , phagocytosis , flow cytometry , staphylococcus aureus , biology , microbiology and biotechnology , gene , bacteria , biochemistry , genetics

The aim of this study was to explore the pathogenic mechanism of group A Streptococcus (GAS) and to investigate how GAS evades phagocytosis by immune cells.

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