The complexity of diagnosing latent tuberculosis infection in older adults in long-term care facilities | Zendy

Natasha S. Hochberg | Zendy; Sergey Rekhtman | Zendy; Julianne E. Burns | Zendy; Lisa GanleyLeal | Zendy; Sina Helbig | Zendy; Nathaniel S. Watts | Zendy; Gary H. Brandeis | Zendy; Jerrold J. Ellner | Zendy; C. Robert Horsburgh | Zendy

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The complexity of diagnosing latent tuberculosis infection in older adults in long-term care facilities

Author(s) -

Natasha S. Hochberg,

Sergey Rekhtman,

Julianne E. Burns,

Lisa GanleyLeal,

Sina Helbig,

Nathaniel S. Watts,

Gary H. Brandeis,

Jerrold J. Ellner,

C. Robert Horsburgh

Publication year - 2016

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2016.01.007

Subject(s) - medicine , tuberculin , tuberculosis , latent tuberculosis , mycobacterium tuberculosis , immunology , reversion , pathology , biology , biochemistry , gene , phenotype

In the USA, tuberculosis disease rates are highest in older adults. Diagnostic testing for latent tuberculosis infection (LTBI) has not been evaluated carefully in this group. The aim of this study was to define the relationship between tuberculin skin test (TST) results, T-SPOT.TB results, and T-cell responses to Mycobacterium tuberculosis antigens.

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