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Dynamics of immune parameters during the treatment of active tuberculosis showing negative interferon gamma response at the time of diagnosis
Author(s) -
Ikumi Matsushita,
Nguyen Thi Le Hang,
Le Thi Hong,
Do Bang Tam,
Luu Thi Lien,
Pham Huu Thuong,
Vu Cao Cuong,
Minako Hijikata,
Nobuyuki Kobayashi,
Shinsaku Sakurada,
Kazue Higuchi,
Nobuyuki Harada,
Naoto Keicho
Publication year - 2015
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2015.09.021
Subject(s) - medicine , interferon gamma , immune system , tuberculosis , mycobacterium tuberculosis , immunology , interferon , antigen , quantiferon , tuberculosis diagnosis , gastroenterology , pathology , latent tuberculosis
In the performance of interferon gamma release assays (IGRA) for the diagnosis of tuberculosis (TB) infection, false-negative results are a major obstacle. In active TB patients, treatment-dependent changes of the negative test results remain unknown.

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