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The increased severity in patients presenting to hospital with diarrhea in Dhaka, Bangladesh since the emergence of the hybrid strain of Vibrio cholerae O1 is not unique to cholera patients
Author(s) -
Fahima Chowdhury,
Alison Kuchta,
Ashraful Islam Khan,
Abu S. G. Faruque,
Stephen B. Calderwood,
Edward T. Ryan,
Firdausi Qadri
Publication year - 2015
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2015.09.007
Subject(s) - cholera , vibrio cholerae , diarrhea , cholera toxin , medicine , strain (injury) , el tor , vibrionaceae , diarrhoeal disease , cholera vaccine , disease , rotavirus , microbiology and biotechnology , pediatrics , virology , biology , bacteria , genetics
A hybrid strain of Vibrio cholerae O1 El Tor that expresses a classical cholera toxin (CT) emerged in 2001. This hybrid variant rapidly replaced the previous El Tor strain around the world. The global emergence of this variant coincided with anecdotal reports that cholera patients were presenting with more severe dehydration and disease in many locations.

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