HIV and schistosomiasis in rural Zimbabwe: the association of Retinol-binding protein with disease progression, inflammation and mortality
Author(s) -
Sebastian Kotzé,
Rutendo B. L. Zinyama-Gutsire,
Per Kallestrup,
Christine Stabell Benn,
Exnevia Gomo,
Jan Gerstoft,
Govert J. van Dam,
Ole Hartvig Mortensen,
Henrik Ullum,
Christian Erikstrup
Publication year - 2015
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2015.01.015
Subject(s) - schistosomiasis , immunology , retinol binding protein , medicine , immune system , vitamin , inflammation , retinol , biology , helminths
Vitamin A has widespread effects on immune function and is therefore interesting in HIV-infection. Retinol-binding protein (RBP or RBP4) is a negative acute-phase protein and a marker of vitamin A status. Our aim was to investigate the association of RBP with HIV progression, infection with schistosomiasis, inflammatory cytokines, and mortality.
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