Open AccessCan sTREM-1 predict septic shock & death in late-onset neonatal sepsis? A pilot study
Author(s) -
Víctor Arízaga-Ballesteros,
Mario René Alcorta-García,
Lizzeth Carolina Lázaro-Martínez,
Jesús Manuel Amézquita-Gómez,
José Manuel Alanís-Cajero,
Luís Villela,
Fabiola CastorenaTorres,
Víctor J. Díaz
Publication year - 2014
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2014.10.013
Subject(s) - septic shock , neonatal sepsis , medicine , sepsis , shock (circulatory) , severe sepsis , intensive care medicine , pediatrics
The transmembrane glycoprotein TREM-1 triggers an inflammatory response. Its soluble fraction (sTREM-1) has been shown to have diagnostic accuracy for late-onset neonatal sepsis (LONS). Until now, the potential of sTREM-1 to predict septic shock and/or death in septic neonates has not been explored. This study obtained estimates of the incidence and prevalence of septic shock and/or death in septic neonates for future sample size calculations for confirmatory studies and evaluated the feasibility of using sTREM-1 as a predictor of septic shock and/or death in neonates with LONS criteria.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom