Efficacy of real-time polymerase chain reaction for rapid diagnosis of endobronchial tuberculosis
Author(s) -
Gang Hou,
Tao Zhang,
Da-hai Kang,
Wei Wang,
Xuejun Hu,
Qiuyue Wang,
Jian Kang
Publication year - 2014
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2014.04.027
Subject(s) - sputum , medicine , bronchoscopy , biopsy , tuberculosis , mycobacterium tuberculosis , staining , real time polymerase chain reaction , pathology , radiology , biology , biochemistry , gene
The definitive diagnosis of endobronchial tuberculosis (EBTB) is challenging because the disease manifests in various non-specific ways, and acid-fast bacilli (AFB) are often undetectable by sputum smear. The objective of this study was to evaluate the efficacy of real-time PCR of bronchoscopic biopsy specimens for the diagnosis of EBTB.
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