Open AccessModification of CYP2B6-mediated site of metabolism on Artemisinin molecule as a way to prolong its maximal antimalarial efficacy
Author(s) -
Tsyrlov Ib,
Chi-Yuan Woo,
V.P. Martin,
I.N. Shur
Publication year - 2014
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2014.03.784
Subject(s) - artemisinin , chemistry , stereochemistry , in vivo , active site , epoxide , microsome , biochemistry , pharmacology , plasmodium falciparum , in vitro , catalysis , biology , malaria , immunology , microbiology and biotechnology
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