Disseminated Mycobacterium celatum disease with prolonged pulmonary involvement
Author(s) -
Cecilie Blenstrup Patsche,
Erik Svensson,
Christian Wejse
Publication year - 2014
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2014.02.020
Subject(s) - ethambutol , medicine , pyrazinamide , azithromycin , clarithromycin , isoniazid , regimen , disease , ciprofloxacin , mycobacterium tuberculosis , antimycobacterial , tuberculosis , antibiotics , immunology , pathology , microbiology and biotechnology , helicobacter pylori , biology
Mycobacterium celatum is a rare cause of human infection, causing disseminated disease in immunosuppressed individuals. Infections localized to the lungs and the lymph nodes have also been reported in immunocompetent individuals. The existing literature on the subject is limited as are experiences with treatment regimens and durations. In the case presented herein, two different treatment regimens were applied to an immunocompromised HIV-negative patient with primary skin involvement and extensive pulmonary involvement due to suspected relapse on isoniazid, ethambutol, and clarithromycin treatment. The treatment regimen was changed to azithromycin, ciprofloxacin, and pyrazinamide and the treatment duration was prolonged to a total of 24 months, with good effect.
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