Multiple relapses of visceral leishmaniasis in a patient with HIV in India: A treatment challenge | Zendy

Shalom Patole | Zendy; Sakib Burza | Zendy; George M. Varghese | Zendy

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Multiple relapses of visceral leishmaniasis in a patient with HIV in India: A treatment challenge

Author(s) -

Shalom Patole,

Sakib Burza,

George M. Varghese

Publication year - 2014

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2014.02.015

Subject(s) - miltefosine , visceral leishmaniasis , medicine , amphotericin b , leishmaniasis , human immunodeficiency virus (hiv) , antifungal , immunology , dermatology

Visceral Leishmaniasis (VL) is an opportunistic infection amongst HIV-infected people in several endemic countries, and the clinical management of this co-infection poses several challenges. Here we describe a co-infected patient in India who failed to respond to miltefosine monotherapy and subsequently relapsed following two further (different) regimens of liposomal amphotericin B. He was then successfully treated with a combination of 30 mg/kg liposomal amphotericin B and 14 days of 100mg/day oral miltefosine.

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