Open AccessA case of lepromatous leprosy complicated by hemophagocytosis misdiagnosed as hemophagocytic lymphohistiocytosis
Author(s) -
Xiangzong Zeng,
Yini Wang,
Jingshi Wang,
Lin Wu,
Jia Zhang,
Qingyang Wei,
Jian Liu,
Zhao Wang
Publication year - 2014
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2014.02.004
Subject(s) - hemophagocytosis , leprosy , hemophagocytic lymphohistiocytosis , medicine , chronic granulomatous disease , lepromatous leprosy , dermatology , immunology , mycobacterium leprae , incidence (geometry) , population , disease , pathology , environmental health , bone marrow , physics , pancytopenia , optics
Leprosy is an infectious chronic granulomatous disease caused by Mycobacterium leprae. The disease mainly affects the skin, peripheral nerves, mucosa, and viscera. The World Health Organization has reported that most countries with high endemicity have reached the goal of eliminating leprosy (defined as reaching a prevalence of <1 leprosy case per 10 000 population) at the national level, after years of proactive control campaigns. The incidence of leprosy has been decreasing across the globe year by year. However, misdiagnosis happens occasionally due to the complexity of clinical manifestations and lack of physician awareness of this disease. We report a case of lepromatous leprosy complicated by hemophagocytosis misdiagnosed as hemophagocytic lymphohistiocytosis.
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