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Meta-analysis: amantadine may lower the efficacy of pegylated interferon plus ribavirin in treatment-naive hepatitis C genotype 1 patients
Author(s) -
Jian Chen,
Jian Shi,
WeiFen Xie,
Xin Zeng,
Yong Lin
Publication year - 2012
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2012.06.002
Subject(s) - ribavirin , amantadine , pegylated interferon , medicine , hepatitis c , virology , genotype , pharmacology , gastroenterology , chronic hepatitis , virus , biology , biochemistry , gene
The current standard therapy for hepatitis C virus genotype 1 (HCV-1) infection is still suboptimal. Whether adding amantadine (AMA) to pegylated interferon (PEG-IFN) plus ribavirin (RBV) improves the virological response in treatment-naive HCV-1 patients remains unclear.

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