A large epidemic of enterovirus 71 associated hand, foot and mouth disease in southern Vietnam, 2011 | Zendy

Truong Huu Khanh | Zendy; Saraswathy Sabanathan | Zendy; Le Phan Kim Thoa | Zendy; Tang Chi Thuong | Zendy; Jeremy Farrar | Zendy; Tran T. Hien | Zendy; H. Rogier van Doorn | Zendy

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A large epidemic of enterovirus 71 associated hand, foot and mouth disease in southern Vietnam, 2011

Author(s) -

Truong Huu Khanh,

Saraswathy Sabanathan,

Le Phan Kim Thoa,

Tang Chi Thuong,

Jeremy Farrar,

Tran T. Hien,

H. Rogier van Doorn

Publication year - 2012

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2012.05.932

Subject(s) - medicine , enterovirus 71 , pediatrics , outbreak , enterovirus , disease , epidemiology , foot and mouth disease , hand foot and mouth disease , throat , surgery , virology , virus

Background: Enterovirus 71 has emerged as a frequent cause of hand, foot and mouth disease (HFMD) outbreaks in Asia, and is associated with neurologic and cardiopulmonary complications, especially in children under 4 years of age. In 2011, a large outbreak of HFMD hit southern Vietnam from March onward: 110,897 cases and 166 deaths were reported across 63 provinces. A grading system based on clinical symptoms is used to guide interventions. Children with no neurological involvement are classified as grade 1 HFMD and are usually not admitted. Children with myoclonus, observed by parents (grade 2a) or by medical staff (grade 2b) are admitted. Grade 3 and 4 is reserved for children with more severe neurological and cardiopulmonary involvement

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