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Severe tremor due to vancomycin therapy: a case report and literature review
Author(s) -
Luc Benoit,
Margaret Gray,
Wendy Sligl
Publication year - 2012
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2012.03.013
Subject(s) - vancomycin , causality (physics) , intensive care medicine , medicine , antimicrobial , adverse effect , essential tremor , physical medicine and rehabilitation , biology , staphylococcus aureus , physics , quantum mechanics , bacteria , microbiology and biotechnology , genetics
Vancomycin is a popular antimicrobial used to treat a variety of Gram-positive infections. Its side effect profile has been well defined due to its high global utilization as a result of the emergence of antimicrobial-resistant organisms in recent decades. Despite its widespread use, however, various idiosyncratic reactions may occur without adequate or universal reporting. We present a case of severe tremor due to vancomycin that has not been previously reported in the literature. Our patient might have been prone to this adverse effect given an underlying essential tremor. Causality is presumed based on the temporal association, while the pathophysiological link remains elusive.

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