Evaluation of a new interferon-gamma release assay and comparison to tuberculin skin test during a tuberculosis outbreak | Zendy

Qisheng Song | Zendy; HuiShan Guo | Zendy; Hui Zhong | Zendy; Zuoguang Liu | Zendy; Xiuqin Chen | Zendy; Cui Wang | Zendy; Neal Touzjian | Zendy; Yichen Lv | Zendy; Xiwei Lu | Zendy; Qi Wang | Zendy

Open Access

Evaluation of a new interferon-gamma release assay and comparison to tuberculin skin test during a tuberculosis outbreak

Author(s) -

Qisheng Song,

HuiShan Guo,

Hui Zhong,

Zuoguang Liu,

Xiuqin Chen,

Cui Wang,

Neal Touzjian,

Yichen Lv,

Xiwei Lu,

Qi Wang

Publication year - 2012

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2012.03.003

Subject(s) - tuberculin , tuberculosis , skin test , outbreak , tuberculin test , medicine , virology , interferon gamma release assay , immunology , interferon gamma , mycobacterium tuberculosis , pathology , latent tuberculosis , cytokine

The tuberculin skin test (TST) is commonly used for the diagnosis of latent tuberculosis infection (LTBI) in non-bacille Calmette-Guérin (BCG) vaccination settings. In recent years, attention has been drawn to interferon-gamma release assays (IGRAs), especially in BCG-vaccinated populations. In this study, we evaluated the TST and a new whole blood IGRA in BCG-vaccinated individuals during a tuberculosis (TB) outbreak in China.

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