The effect of metformin on the efficacy of antiviral therapy in patients with genotype 1 chronic hepatitis C and insulin resistance | Zendy

JianWu Yu | Zendy; Lijie Sun | Zendy; Yong-Hua Zhao | Zendy; Peng Kang | Zendy; BingZhu Yan | Zendy

Open Access

The effect of metformin on the efficacy of antiviral therapy in patients with genotype 1 chronic hepatitis C and insulin resistance

Author(s) -

JianWu Yu,

Lijie Sun,

Yong-Hua Zhao,

Peng Kang,

BingZhu Yan

Publication year - 2012

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2012.02.004

Subject(s) - ribavirin , medicine , gastroenterology , metformin , insulin resistance , chronic hepatitis , genotype , incidence (geometry) , diarrhea , insulin , immunology , virus , biology , biochemistry , physics , optics , gene

Insulin resistance (IR) affects sustained virological response (SVR) in chronic hepatitis C (CHC). The aim of this study was to investigate the effect of adding metformin to peginterferon alfa-2a and ribavirin on the efficacy in patients with genotype 1 CHC and IR.

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