Genetic polymorphisms and serum levels of mannose-binding lectin in Chinese pediatric patients with common infectious diseases | Zendy

Ran Tao | Zendy; ChunZhen Hua | Zendy; Yingzi Hu | Zendy; Shiqiang Shang | Zendy

Open Access

Genetic polymorphisms and serum levels of mannose-binding lectin in Chinese pediatric patients with common infectious diseases

Author(s) -

Ran Tao,

ChunZhen Hua,

Yingzi Hu,

Shiqiang Shang

Publication year - 2012

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2012.01.014

Subject(s) - mannan binding lectin , immunology , genotype , medicine , allele , haplotype , biology , lectin , gene , genetics

Mannose-binding lectin (MBL) is a collagen-like serum protein that plays an important role in first-line host defense, especially in infants and young children. The objective of this study was to explore the genetic polymorphisms and serum protein levels of MBL in Chinese pediatric patients with common infectious diseases, including recurrent respiratory infection (RRI), acute respiratory infection (ARI), active cytomegalovirus (CMV) infection, localized abscess, and otitis media.

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