Macrocytosis is a predictor of resting lactate concentrations in persons on dideoxynucleoside therapy for HIV infection | Zendy

Wendy Wobeser | Zendy; Erin E. Morgan | Zendy; Amir Rumman | Zendy; P M Ford | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Macrocytosis is a predictor of resting lactate concentrations in persons on dideoxynucleoside therapy for HIV infection

Author(s) -

Wendy Wobeser,

Erin E. Morgan,

Amir Rumman,

P M Ford

Publication year - 2012

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2011.11.013

Subject(s) - macrocytosis , mean corpuscular volume , mitochondrial toxicity , toxicity , medicine , didanosine , immunology , biology , gastroenterology , hematocrit , antiretroviral therapy , human immunodeficiency virus (hiv) , viral load , anemia

Mitochondrial toxicity is an important toxicity of antiretroviral therapy and may manifest as elevated blood lactate. Macrocytosis has been hypothesized to act as a marker of mitochondrial toxicity in persons with HIV infection. As part of a larger study on markers of mitochondrial toxicity we evaluated the relationship between resting lactate and erythrocyte mean corpuscular volume (MCV).

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research