Evaluation of factors predictive of the prognosis in Crimean-Congo hemorrhagic fever: new suggestions | Zendy

Barış Öztürk | Zendy; Emin Ediz Tütüncü | Zendy; Ferit Kuşçu | Zendy; Yunus Gürbüz | Zendy; İrfan Şencan | Zendy; Hakan Tüzün | Zendy

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Evaluation of factors predictive of the prognosis in Crimean-Congo hemorrhagic fever: new suggestions

Author(s) -

Barış Öztürk,

Emin Ediz Tütüncü,

Ferit Kuşçu,

Yunus Gürbüz,

İrfan Şencan,

Hakan Tüzün

Publication year - 2011

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2011.06.005

Subject(s) - medicine , partial thromboplastin time , gastroenterology , crimean–congo hemorrhagic fever , prothrombin time , creatine kinase , myalgia , white blood cell , c reactive protein , fibrinogen , alanine transaminase , lactate dehydrogenase , lymphocytopenia , leukopenia , antithrombin , lymphocyte , immunology , platelet , biochemistry , chemistry , disease , chemotherapy , inflammation , enzyme , heparin

Crimean-Congo hemorrhagic fever (CCHF) is one of the viral hemorrhagic fevers caused by tick bites. Common symptoms of the infection are fatigue, high fever, headache, and myalgia. In some patients hemorrhage may accompany these symptoms and is a sign of a poor prognosis. Typical laboratory changes are thrombocytopenia, leukopenia, elevation of aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine phosphokinase (CPK), and lactate dehydrogenase (LDH), and prolongation of prothrombin time (PT) and activated partial thromboplastin time (aPTT). Mortality rates vary between 3% and 30%. The aim of this study was to determine the factors affecting the prognosis of CCHF.

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