Cryptococcal immune reconstitution syndrome during steroid withdrawal treated with hydroxychloroquine | Zendy

Shivakumar Narayanan | Zendy; Chandralekha Banerjee | Zendy; Peter A. Holt | Zendy

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Cryptococcal immune reconstitution syndrome during steroid withdrawal treated with hydroxychloroquine

Author(s) -

Shivakumar Narayanan,

Chandralekha Banerjee,

Peter A. Holt

Publication year - 2010

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2010.09.006

Subject(s) - hydroxychloroquine , immune system , medicine , antifungal , immunology , human immunodeficiency virus (hiv) , dermatology , covid-19 , disease , infectious disease (medical specialty)

We present a case report of cryptococcal immune reconstitution syndrome (IRS), in a non HIV infected patient, which we treated with hydroxychloroquine with successful results. We briefly review cryptococcal IRS, possible mechanisms of action of hydroxychloroquine as an immunomodulatory agent, and its potential role in management of IRS.

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