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An increase in non-toxigenic Corynebacterium diphtheriae infections in Poland — molecular epidemiology and antimicrobial susceptibility of strains isolated from past outbreaks and those currently circulating in Poland
Author(s) -
Aleksandra Anna Zasada,
Milena Baczewska-Rej,
Sebastian Wardak
Publication year - 2010
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2010.05.013
Subject(s) - corynebacterium diphtheriae , microbiology and biotechnology , biology , pulsed field gel electrophoresis , virology , linezolid , genotype , diphtheria , vancomycin , vaccination , staphylococcus aureus , genetics , bacteria , gene
An increase in non-toxigenic Corynebacterium diphtheriae infections--mainly invasive infections--has been observed in countries with high vaccination coverage. However, reasons for this situation are unknown. In this study we characterized and compared human clinical isolates of non-toxigenic C. diphtheriae strains isolated from infections that have occurred over recent years and C. diphtheriae strains isolated from diphtheria cases from past outbreaks in Poland.

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