Infectious complications in patients with acute myeloid leukemia treated according to the protocol with daunorubicin and cytarabine with or without addition of cladribine. A multicenter study by the Polish Adult Leukemia Group (PALG)
Author(s) -
Ewa LechMarańda,
Marek Seweryn,
Sebastian Giebel,
Jerzy Hołowiecki,
Beata PiątkowskaJakubas,
Joanna Węgrzyn,
Aleksander B. Skotnicki,
Marek Kiełbiński,
Kazimierz Kuliczkowski,
Monika Paluszewska,
W Wiktor-Jędrzejczak,
Magdalena Dutka,
Andrzej Hellmann,
Marcin Flont,
Barbara Zdziarska,
Grażyna Pałynyczko,
L Konopka,
Tomasz Szpila,
Krzysztof Gawroński,
K Sułek,
J Sokołowski,
Janusz Kłoczko,
Krzysztof Warzocha,
Tadeusz Robak
Publication year - 2009
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2009.02.021
Subject(s) - daunorubicin , cladribine , medicine , cytarabine , myeloid leukemia , leukemia , oncology
The addition of cladribine to the standard regimen consisting of daunorubicin and cytarabine has been reported to increase the efficacy of induction therapy in acute myeloid leukemia (AML). The goal of this study was to determine the effect of this modification on the incidence and spectrum of infectious complications.
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