Open AccessUtility of 16S ribosomal DNA sequencing in the diagnosis of Staphylococcus lugdunensis native valve infective endocarditis: case report and literature review
Author(s) -
Surinder Pada,
David Chien Lye,
YeeSin Leo,
Timothy Barkham
Publication year - 2009
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2009.02.019
Subject(s) - staphylococcus lugdunensis , infective endocarditis , microbiology and biotechnology , ribosomal dna , endocarditis , dna sequencing , staphylococcus aureus , medicine , biology , genetics , dna , staphylococcus , bacteria , phylogenetics , gene
We report a case of possible infective endocarditis without fever presenting with an acutely ischemic limb with prior antimicrobial therapy preventing identification by culture of a microorganism. 16S ribosomal DNA sequencing led to the identification of Staphylococcus lugdunensis from an embolus removed at surgery and subsequent successful antibiotic treatment. We review the utility of 16S ribosomal DNA sequencing in diagnosing infective endocarditis and other infectious conditions.
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