Occult hepatitis B virus infection in patients with isolated core antibody and HIV co-infection in an urban clinic in Johannesburg, South Africa | Zendy

Cynthia Firnhaber | Zendy; Raquel Viana | Zendy; Anne Reyneke | Zendy; Doreen Schultze | Zendy; Babatyi MalopeKgokong | Zendy; Mhairi Maskew | Zendy; Adrian M. Di Bisceglie | Zendy; Patrick MacPhail | Zendy; Ian Sanne | Zendy; Michael C. Kew | Zendy

Open Access

Occult hepatitis B virus infection in patients with isolated core antibody and HIV co-infection in an urban clinic in Johannesburg, South Africa

Author(s) -

Cynthia Firnhaber,

Raquel Viana,

Anne Reyneke,

Doreen Schultze,

Babatyi MalopeKgokong,

Mhairi Maskew,

Adrian M. Di Bisceglie,

Patrick MacPhail,

Ian Sanne,

Michael C. Kew

Publication year - 2008

Publication title -

international journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.278

H-Index - 89

eISSN - 1878-3511

pISSN - 1201-9712

DOI - 10.1016/j.ijid.2008.08.018

Subject(s) - hbsag , medicine , hepatitis b virus , occult , serology , virology , viral load , antibody , hepatitis b , immunology , virus , pathology , alternative medicine

The prevalence of HIV/hepatitis B virus (HBV) co-infection in South Africa ranges from 4.8% to 17% using the standard marker surface antigen (hepatitis B surface antigen, HBsAg) for chronic active HBV infection. However, sensitive molecular techniques for detecting HBV DNA in serum can detect occult HBV infection. We report the first observational prospective study of occult HBV infection in HIV-positive people in South Africa.

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