Open AccessSalivary gland transcriptome analysis during Plasmodium infection in malaria vector Anopheles stephensi
Author(s) -
Rajnikant Dixit,
Arun Sharma,
Devendra T. Mourya,
Kamaraju Raghavendra,
Millind S. Patole,
Yogesh S. Shouche
Publication year - 2009
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2008.07.027
Subject(s) - anopheles stephensi , biology , transcriptome , anopheles gambiae , parasite hosting , expressed sequence tag , salivary gland , anopheles , malaria , genetics , gene , alternative splicing , virology , genome , immunology , gene expression , aedes aegypti , biochemistry , botany , larva , world wide web , computer science , messenger rna
Understanding the tissue-specific molecular cross-talk mechanism during the mosquito-parasite interaction is of prime importance in the design of new strategies for malaria control. Because mosquito salivary glands are the final destination for the parasite maturation and transmission of vector-borne diseases, identification and characterization of salivary genes and their products are equally important in order to access their effect on the infectivity of the parasite. During the last five years there have been several studies on the sialomes of Anopheles mosquitoes, however very limited information is available on the changes in the salivary gland transcriptome in the presence of Plasmodium, and this information is limited to the mosquito Anopheles gambiae.
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