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Prevalent phenotypes and antibiotic resistance in Escherichia coli and Klebsiella pneumoniae at an Indian tertiary care hospital: plasmid-mediated cefoxitin resistance
Author(s) -
Mohammad Shahid,
A Malik,
Mohammad Akram,
Lalit Agrawal,
Asad U. Khan,
Manisha Agrawal
Publication year - 2007
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2007.08.008
Subject(s) - amikacin , cefoxitin , klebsiella pneumoniae , microbiology and biotechnology , cefotaxime , tobramycin , cephalosporin , population , biology , gentamicin , antibiotics , antibiotic resistance , escherichia coli , medicine , bacteria , staphylococcus aureus , biochemistry , genetics , environmental health , gene
The beta-lactam antibiotics, in combination with aminoglycosides, are among the most widely prescribed antibiotics. However, because of extensive and unnecessary use, resistance to these drugs continues to increase. In recent years, resistance in the Indian bacterial population has increased markedly, the majority showing complex mechanisms. Due to increased transcontinental movement of the human population, it would be wise to know the prevalence and resistance complexity of these strains, well in advance, in order to formulate a policy for empirical therapy.

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