Rate of YMDD motif mutants in lamivudine-untreated Iranian patients with chronic hepatitis B virus infection
Author(s) -
Amitis Ramezani,
Ali Akbar Velayati,
Mohammad Reza Hasanjani Roshan,
Latif Gachkar,
Mohammad Banifazl,
Hossein Keyvani,
Arezoo Aghakhani
Publication year - 2008
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2007.08.003
Subject(s) - lamivudine , medicine , virology , hbeag , chronic hepatitis , hepatitis b virus , virus , mutant , hepatitis b , gastroenterology , biology , gene , hbsag , genetics
Lamivudine is used for the treatment of chronic hepatitis B patients. Recent studies show that the YMDD motif mutants (resistant hepatitis B virus) occur as natural genome variability in lamivudine-untreated chronic hepatitis B patients. In this study we aimed to determine the rate of YMDD motif mutants in lamivudine-untreated chronic hepatitis B patients in Iran.
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