Open AccessProphylactic effect of the anti-inflammatory drug diclofenac in experimental schistosomiasis mansoni
Author(s) -
Nevine Nessim,
Soheir Mahmoud
Publication year - 2006
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2006.01.004
Subject(s) - diclofenac , schistosomiasis , medicine , schistosoma mansoni , granuloma , regimen , niridazole , drug , pharmacology , immunology , gastroenterology , helminths
This study was a trial to demonstrate the prophylactic effect of diclofenac, a widely used anti-inflammatory drug (diclofenac potassium, CAS-15307-81-0, Ciba Geigy, 334.2) in experimental schistosomiasis mansoni. Two different dose regimens were used to explore the effects upon worm load, tissue egg load, and hepatic granuloma size.
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