Open AccessHyaluronidase augments pneumolysin-mediated injury to human ciliated epithelium
Author(s) -
Charles Feldman,
Riana Cockeran,
M.J. Jedrzejas,
Timothy J. Mitchell,
Ronald Anderson
Publication year - 2006
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2005.09.002
Subject(s) - pneumolysin , hyaluronidase , epithelium , respiratory epithelium , biology , pathology , medicine , microbiology and biotechnology , streptococcus pneumoniae , biochemistry , enzyme , antibiotics
The main objective of this study was to investigate the effects of pneumococcal hyaluronidase (0.1-10microg/ml), alone and in combination with pneumolysin (50 and 100ng/ml), on human ciliated epithelium.
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