The effect of treatment with moxifloxacin or azithromycin on acute bacterial rhinosinusitis in mice
Author(s) -
Thongchai Luxameechanporn,
Christopher Blair,
Virat Kirtsreesakul,
Kim D. Thompson,
Robert M. Naclerio
Publication year - 2006
Publication title -
international journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 89
eISSN - 1878-3511
pISSN - 1201-9712
DOI - 10.1016/j.ijid.2005.07.007
Subject(s) - azithromycin , moxifloxacin , medicine , microbiology and biotechnology , antibiotics , biology
Acute bacterial rhinosinusitis, which is a major health problem, is treated with antibiotics. We developed a mouse model of acute bacterial rhinosinusitis to gain a better understanding of the pathophysiology of the disease. Our goal was to investigate the response to acute rhinosinusitis when treated with either a bactericidal or a bacteriostatic antibiotic.
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