Neisseria meningitidis and cytomegalovirus simultaneous detection in the filmarray meningitis/encephalitis panel and its clinical relevance | Zendy

Nadav Sorek | Zendy; Shai Ashkenazi | Zendy; Gilat Livni | Zendy; Haim BenZvi | Zendy

Open Access

Neisseria meningitidis and cytomegalovirus simultaneous detection in the filmarray meningitis/encephalitis panel and its clinical relevance

Author(s) -

Nadav Sorek,

Shai Ashkenazi,

Gilat Livni,

Haim BenZvi

Publication year - 2019

Publication title -

idcases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.319

H-Index - 13

ISSN - 2214-2509

DOI - 10.1016/j.idcr.2019.e00516

Subject(s) - medicine , neisseria meningitidis , meningitis , encephalitis , virology , viral meningitis , cytomegalovirus , clinical significance , microbiology and biotechnology , immunology , bacterial meningitis , virus , viral disease , herpesviridae , pathology , biology , pediatrics , bacteria , genetics

A BioFire FilmArray Meningitis/Encephalitis test was performed on a 7-month old child suspected for bacterial meningitis. Two pathogens were detected, Neisseria meningitidis and cytomegalovirus (CMV). We verified the filmarray meningitis/encephalitis test by pan-bacterial assay to test for Neisseria meningitidis and CMV viral load test for the CMV detection. Pan-bacterial confirmed presence of N. meningitidis, but CMV was not detected by the CMV viral load test. Together with the manifestations of high fever, vomiting, diffuse petechial rash, bulging fontanel, and leukocytosis, it is a clear case of meningococcal meningitis, while CMV detection had no clinical relevance.

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