Is there a role for prophylaxis against atrial fibrillation for patients undergoing lung surgery?
Author(s) -
Vivek Shrivastava,
Brian Nyawo,
Joel Dunning,
G N Morritt
Publication year - 2004
Publication title -
interactive cardiovascular and thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 56
eISSN - 1569-9293
pISSN - 1569-9285
DOI - 10.1016/j.icvts.2004.08.002
Subject(s) - medicine , atrial fibrillation , randomized controlled trial , diltiazem , cardiothoracic surgery , clinical trial , cardiac surgery , surgery , intensive care medicine , anesthesia , cardiology , calcium
A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed whether prophylactic anti-arrhythmic drugs may prevent atrial fibrillation (AF) following lung resection. Altogether 457 papers were found using the reported search, of which 14 presented the best evidence to answer the clinical question. The author, journal, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. We identified single randomized trials that have demonstrated a benefit for Diltiazem, Bupivacaine epidural and magnesium for prophylaxis against AF in patients undergoing non-cardiac thoracic surgery, with a number needed to treat of between 4 and 8 with these regimes.
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